Phosphodiesterase in a sentence

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Phosphodiesterase in a sentence

(1) Sildenafil is a phosphodiesterase type 5 inhibitor.

(2) The inhibition of phosphodiesterase can lead to vasodilation.

(3) Phosphodiesterase is an important target for drug development.

(4) Phosphodiesterase activity can be modulated by small molecules.

(5) Phosphodiesterase is found in various tissues throughout the body.

(6) Phosphodiesterase activity is regulated by phosphorylation events.

(7) Certain medications work by inhibiting phosphodiesterase activity.

(8) Phosphodiesterase activity can be influenced by genetic variations.

(9) The activity of phosphodiesterase can be inhibited by certain drugs.

(10) Phosphodiesterase is involved in the regulation of cardiac function.



Phosphodiesterase sentence

(11) Phosphodiesterase is an enzyme that hydrolyzes phosphodiester bonds.

(12) The activity of phosphodiesterase can be influenced by changes in pH.

(13) The function of phosphodiesterase is to break down cyclic nucleotides.

(14) Mutations in the phosphodiesterase gene can lead to genetic disorders.

(15) The activity of phosphodiesterase can be modulated by various factors.

(16) Phosphodiesterase activity can be regulated by phosphorylation events.

(17) The role of phosphodiesterase in cardiac function is well-established.

(18) Phosphodiesterase inhibitors have been used in the treatment of asthma.

(19) The activity of phosphodiesterase can be measured using specific assays.

(20) The activity of phosphodiesterase can be affected by genetic variations.




Phosphodiesterase make sentence

(21) Phosphodiesterase is involved in the regulation of platelet aggregation.

(22) Phosphodiesterase breaks down cyclic nucleotides, such as cAMP and cGMP.

(23) Phosphodiesterase inhibitors have been used to treat symptoms of asthma.

(24) The activity of phosphodiesterase can be influenced by hormonal signals.

(25) The activity of phosphodiesterase can be altered by environmental factors.

(26) The role of phosphodiesterase in neuronal signaling is still being studied.

(27) The regulation of phosphodiesterase activity is tightly controlled in cells.

(28) Phosphodiesterase is involved in the degradation of intracellular messengers.

(29) The expression of phosphodiesterase is upregulated in certain disease states.

(30) Phosphodiesterase is involved in the regulation of smooth muscle contraction.



Sentence of phosphodiesterase

(31) Phosphodiesterase plays a role in the regulation of smooth muscle contraction.

(32) The activity of phosphodiesterase can be influenced by changes in temperature.

(33) Phosphodiesterase is an important enzyme in the regulation of immune responses.

(34) Phosphodiesterase inhibitors have been shown to have anti-inflammatory effects.

(35) The activity of phosphodiesterase can be modulated by various signaling pathways.

(36) Phosphodiesterase activity is essential for maintaining normal cellular signaling.

(37) Phosphodiesterase is an important target for drug development in various diseases.

(38) Phosphodiesterase inhibitors have been used to treat symptoms of Raynaud's disease.

(39) The role of phosphodiesterase in immune cell function is still not fully understood.

(40) The inhibition of phosphodiesterase can lead to increased levels of cyclic nucleotides.




Phosphodiesterase meaningful sentence

(41) Phosphodiesterase inhibitors are commonly used in the treatment of erectile dysfunction.

(42) The activity of phosphodiesterase is tightly regulated to maintain cellular homeostasis.

(43) The inhibition of phosphodiesterase can enhance the effects of certain neurotransmitters.

(44) Phosphodiesterase is an enzyme that plays a crucial role in regulating cellular processes.

(45) The discovery of phosphodiesterase isoforms has opened up new avenues for drug development.

(46) The enzyme phosphodiesterase plays a crucial role in regulating cellular signaling pathways.

(47) Phosphodiesterase inhibitors have shown promise in the treatment of certain types of cancer.

(48) Phosphodiesterase activity is crucial for the termination of signaling cascades in the body.

(49) Phosphodiesterase 3 inhibitors are used to treat heart failure and improve cardiac function.

(50) The inhibition of phosphodiesterase can lead to increased levels of intracellular messengers.



Phosphodiesterase sentence examples

(51) The regulation of phosphodiesterase activity is crucial for maintaining cellular homeostasis.

(52) Phosphodiesterase inhibitors have been investigated for their potential role in cancer therapy.

(53) The discovery of phosphodiesterase enzymes opened up new avenues for therapeutic interventions.

(54) Phosphodiesterase activity is tightly regulated by phosphorylation and dephosphorylation events.

(55) The inhibition of phosphodiesterase 2 has shown promise in the treatment of respiratory diseases.

(56) The discovery of phosphodiesterase enzymes revolutionized our understanding of cellular signaling.

(57) Phosphodiesterase inhibitors have been investigated as potential treatments for Alzheimer's disease.

(58) Phosphodiesterase 10 inhibitors are being explored as potential treatments for psychiatric disorders.

(59) Phosphodiesterase inhibitors have shown promising results in the treatment of certain types of cancer.

(60) The discovery of phosphodiesterase inhibitors has revolutionized the treatment of erectile dysfunction.



Sentence with phosphodiesterase

(61) The inhibition of phosphodiesterase 9 has shown promise in the treatment of neurodegenerative disorders.

(62) Phosphodiesterase 7 inhibitors have been investigated as potential therapeutics for autoimmune diseases.

(63) Phosphodiesterase inhibitors have been shown to improve symptoms in patients with pulmonary hypertension.

(64) Phosphodiesterase activity can be modulated by various factors, including hormones and neurotransmitters.

(65) Phosphodiesterase 4 inhibitors have been investigated as potential therapeutics for inflammatory diseases.

(66) The enzyme phosphodiesterase plays a crucial role in regulating intracellular levels of cyclic nucleotides.

(67) The discovery of phosphodiesterase enzymes revolutionized our understanding of cellular signaling pathways.

(68) Phosphodiesterase inhibitors have been investigated as potential treatments for neurodegenerative diseases.

(69) Phosphodiesterase inhibitors have been shown to enhance memory and cognitive function in preclinical studies.

(70) Phosphodiesterase 11 is a relatively new isoform that is still being studied for its physiological functions.




Use phosphodiesterase in a sentence

(71) The phosphodiesterase enzyme is responsible for the breakdown of cyclic nucleotides into their inactive forms.

(72) The dysregulation of phosphodiesterase activity has been linked to the development of cardiovascular diseases.

(73) Phosphodiesterase activity is crucial for maintaining the balance between cellular proliferation and apoptosis.

(74) The dysregulation of phosphodiesterase activity has been implicated in the pathogenesis of metabolic disorders.

(75) Phosphodiesterase 6 inhibitors are being investigated as potential treatments for retinal degenerative diseases.

(76) The dysregulation of phosphodiesterase activity has been implicated in the pathogenesis of neurological disorders.

(77) Phosphodiesterase inhibitors have been studied for their potential role in improving memory and cognitive function.

(78) Phosphodiesterase inhibitors have been used experimentally to study the role of cyclic nucleotides in cellular processes.

(79) The development of selective phosphodiesterase inhibitors has greatly improved the treatment options for various diseases.

(80) Phosphodiesterase 5 inhibitors, such as Viagra, are widely prescribed for the treatment of pulmonary arterial hypertension.



Phosphodiesterase meaning


Phosphodiesterase is a term that refers to a group of enzymes responsible for breaking down phosphodiester bonds in molecules. These enzymes play a crucial role in various biological processes, including signal transduction, cell division, and metabolism. Understanding how to use the word "phosphodiesterase" or the phrase "phosphodiesterase inhibitor" in a sentence can be helpful in scientific discussions or when studying related fields such as pharmacology or biochemistry. Here are some tips on how to incorporate this term effectively:


1. Define the term: When introducing the word "phosphodiesterase" or the phrase "phosphodiesterase inhibitor" in a sentence, it is essential to provide a brief definition or explanation.

For example, "Phosphodiesterase is an enzyme that catalyzes the hydrolysis of phosphodiester bonds in molecules."


2. Contextualize the term: To enhance understanding, it is beneficial to provide context or examples related to the term. For instance, "Phosphodiesterase inhibitors are commonly used in the treatment of erectile dysfunction, as they prevent the breakdown of cyclic guanosine monophosphate (cGMP) and promote smooth muscle relaxation."


3. Use in scientific discussions: When discussing scientific research or findings, incorporating the term "phosphodiesterase" or "phosphodiesterase inhibitor" can demonstrate a deeper understanding of the topic.

For example, "The study aimed to investigate the effects of a novel phosphodiesterase inhibitor on neuronal signaling pathways."


4. Relate to pharmacology: In the field of pharmacology, the term "phosphodiesterase inhibitor" is frequently used. When discussing drug mechanisms or interactions, it is crucial to use the term accurately. For instance, "The administration of a phosphodiesterase inhibitor resulted in increased levels of intracellular cAMP, leading to bronchodilation in patients with asthma."


5. Discuss clinical applications: Phosphodiesterase inhibitors have various clinical applications, and incorporating these applications in sentences can provide practical examples.

For example, "Phosphodiesterase inhibitors, such as sildenafil, are commonly prescribed to patients with pulmonary arterial hypertension to improve exercise capacity and reduce symptoms."


6. Highlight research advancements: When discussing recent scientific advancements or breakthroughs related to phosphodiesterase, using the term in sentences can showcase up-to-date knowledge. For instance, "A recent study identified a novel phosphodiesterase variant that exhibits increased specificity towards cyclic adenosine monophosphate (cAMP), opening new avenues for targeted drug development."


7. Emphasize mechanism of action: Phosphodiesterase inhibitors exert their effects by inhibiting the breakdown of cyclic nucleotides, such as cAMP or cGMP. When discussing their mechanism of action, incorporating the term "phosphodiesterase" can be helpful.

For example, "By inhibiting phosphodiesterase activity, the drug prolongs the action of cGMP, leading to vasodilation and improved blood flow."


8. Compare and contrast: When comparing different types of phosphodiesterase inhibitors or discussing their varying effects, using the term in sentences can aid in clear communication. For instance, "Selective phosphodiesterase type 5 inhibitors, such as tadalafil, have been shown to have a longer duration of action compared to non-selective inhibitors."


In conclusion, incorporating the term "phosphodiesterase" or the phrase "phosphodiesterase inhibitor" in sentences requires a clear understanding of its definition, context, and applications. By following these tips, you can effectively use this word or phrase in scientific discussions, pharmacological explanations, and other related contexts.





The word usage examples above have been gathered from various sources to reflect current and historical usage of the word Phosphodiesterase. They do not represent the opinions of TranslateEN.com.