Proinsulin in a sentence
(1) The production of proinsulin occurs in the pancreas.
(2) Mutations in the proinsulin gene can lead to diabetes.
(3) Proinsulin undergoes enzymatic cleavage to form insulin.
(4) Proinsulin is synthesized as a single polypeptide chain.
(5) The proinsulin gene is located on chromosome 11 in humans.
(6) Proinsulin is an important regulator of glucose metabolism.
(7) Proinsulin is synthesized in the beta cells of the pancreas.
(8) Proinsulin is an important biomarker for diagnosing diabetes.
(9) Proinsulin is stored in secretory granules until it is needed.
(10) Proinsulin levels can be measured using immunoassay techniques.
Proinsulin sentence
(11) Proinsulin is involved in the regulation of glucose metabolism.
(12) Proinsulin is an important biomarker for diagnosing insulinomas.
(13) The zymogen proinsulin is converted into insulin in the pancreas.
(14) The structure of proinsulin consists of an A chain and a B chain.
(15) Proinsulin is a precursor molecule that is converted into insulin.
(16) Proinsulin is cleaved into insulin and C peptide during secretion.
(17) Beta cells are responsible for converting proinsulin into insulin.
(18) The proinsulin molecule has a higher molecular weight than insulin.
(19) The proinsulin molecule is larger than the mature insulin molecule.
(20) Proinsulin levels can be elevated in conditions such as insulinoma.
Proinsulin make sentence
(21) Proinsulin is secreted in response to elevated blood glucose levels.
(22) The conversion of proinsulin to insulin occurs in secretory granules.
(23) Proinsulin is processed by the Golgi apparatus before being released.
(24) The proinsulin molecule is highly conserved across different species.
(25) The proinsulin molecule is synthesized as a single polypeptide chain.
(26) Proinsulin levels are elevated in individuals with insulin resistance.
(27) Proinsulin is packaged into vesicles for release into the bloodstream.
(28) The proinsulin molecule is highly stable and resistant to degradation.
(29) The production of proinsulin occurs in the beta cells of the pancreas.
(30) The production of proinsulin is an essential step in insulin synthesis.
Sentence of proinsulin
(31) Proinsulin is released into the bloodstream in response to food intake.
(32) Proinsulin is converted to insulin through a series of enzymatic steps.
(33) The proinsulin molecule consists of an A chain, B chain, and C-peptide.
(34) The secretion of proinsulin is regulated by glucose levels in the blood.
(35) Proinsulin is a key player in the regulation of carbohydrate metabolism.
(36) Proinsulin is cleaved at specific sites to remove the C-peptide segment.
(37) Mutations in the proinsulin gene can lead to impaired insulin production.
(38) Proinsulin is an essential component of the insulin biosynthesis pathway.
(39) The conversion of proinsulin to insulin is crucial for glucose regulation.
(40) Proinsulin is processed by specific enzymes called prohormone convertases.
Proinsulin meaningful sentence
(41) Proinsulin is stored in secretory granules until it is needed for release.
(42) Proinsulin undergoes a series of enzymatic cleavage steps to form insulin.
(43) Proinsulin is stored in secretory vesicles until it is needed for release.
(44) The proinsulin molecule is transported to the cell membrane for secretion.
(45) Proinsulin is synthesized in the endoplasmic reticulum of pancreatic cells.
(46) The conversion of proinsulin to insulin is facilitated by specific enzymes.
(47) Proinsulin is an important target for therapeutic interventions in diabetes.
(48) Proinsulin is synthesized as a larger precursor protein called preproinsulin.
(49) Proinsulin levels can be measured in the blood to assess pancreatic function.
(50) Proinsulin undergoes a series of enzymatic cleavage reactions to form insulin.
Proinsulin sentence examples
(51) The proinsulin molecule contains disulfide bonds that stabilize its structure.
(52) Proinsulin is an important biomarker for diagnosing certain types of diabetes.
(53) Proinsulin is an essential hormone for maintaining normal blood glucose levels.
(54) Proinsulin levels can be measured in blood tests to assess pancreatic function.
(55) Proinsulin is cleaved by prohormone convertase 1 to form insulin and C-peptide.
(56) Proinsulin is synthesized in the endoplasmic reticulum of pancreatic beta cells.
(57) The proinsulin molecule plays a crucial role in maintaining glucose homeostasis.
(58) The ratio of proinsulin to insulin can provide insights into insulin resistance.
(59) The ratio of proinsulin to insulin can be used as a marker for beta cell function.
(60) Insulin therapy aims to replace the deficiency of proinsulin in diabetes patients.
Sentence with proinsulin
(61) The proinsulin molecule contains disulfide bonds that help stabilize its structure.
(62) Proinsulin is processed differently in individuals with type 1 and type 2 diabetes.
(63) The proinsulin to insulin conversion occurs in secretory vesicles within beta cells.
(64) Proinsulin is secreted into the bloodstream in response to high blood glucose levels.
(65) Proinsulin is an important target for therapeutic interventions in diabetes research.
(66) Proinsulin is converted into insulin through a series of proteolytic cleavage events.
(67) Insulin therapy aims to replace the function of proinsulin in individuals with diabetes.
(68) The conversion of proinsulin to insulin is catalyzed by the enzyme prohormone convertase.
(69) The proinsulin molecule is synthesized as part of a larger precursor called preproinsulin.
(70) Proinsulin is packaged into secretory granules before being released into the bloodstream.
Use proinsulin in a sentence
(71) The proinsulin molecule is folded into its native conformation in the endoplasmic reticulum.
(72) The proinsulin molecule is an important target for understanding the pathogenesis of diabetes.
(73) Proinsulin is transported from the endoplasmic reticulum to the Golgi apparatus for processing.
(74) The proinsulin molecule undergoes post-translational modifications before becoming active insulin.
(75) The proinsulin molecule is processed differently in response to different physiological conditions.
(76) The proinsulin to insulin conversion is regulated by various factors, including glucose and hormones.
(77) The proinsulin molecule contains a signal peptide that directs its transport to the secretory pathway.
(78) Proinsulin is transported from the endoplasmic reticulum to the Golgi apparatus for further processing.
(79) Proinsulin is synthesized as a single polypeptide chain that undergoes post-translational modifications.
Proinsulin meaning
Proinsulin is a term that refers to a protein precursor of insulin, which is produced in the pancreas. It plays a crucial role in the regulation of blood sugar levels and is an essential component in the management of diabetes. If you are looking to incorporate the word "proinsulin" or the phrase "proinsulin protein" into your sentences, here are some tips to help you do so effectively:
1. Define the term: When introducing the word "proinsulin" in a sentence, it is important to provide a brief definition or explanation of its meaning.
For example, "Proinsulin, a protein precursor of insulin, is synthesized in the pancreas and undergoes further processing to produce active insulin."
2. Contextualize its significance: To enhance the understanding of the word or phrase, it is helpful to provide some context or background information. For instance, "In individuals with type 2 diabetes, the production of proinsulin is often impaired, leading to an imbalance in insulin levels and subsequent difficulties in glucose regulation."
3. Highlight its role in diabetes management: Since proinsulin is closely associated with insulin, it is essential to emphasize its role in diabetes management.
For example, "The measurement of proinsulin levels in the blood can provide valuable insights into the progression and treatment of diabetes."
4. Discuss its processing and conversion: Proinsulin undergoes enzymatic processing to convert into active insulin. You can mention this process in your sentence to provide a comprehensive understanding. For instance, "After being synthesized, proinsulin is transported to the Golgi apparatus, where it undergoes proteolytic cleavage to yield insulin and C-peptide."
5. Relate it to insulin production: Proinsulin is an integral part of insulin production, so it can be helpful to mention its relationship to insulin in your sentence.
For example, "The efficient conversion of proinsulin to insulin is crucial for maintaining optimal blood glucose levels in individuals with diabetes."
6. Discuss its relevance in research or medical advancements: If you are writing in a scientific or medical context, you can highlight the significance of proinsulin in ongoing research or medical advancements. For instance, "Recent studies have focused on understanding the mechanisms underlying proinsulin misfolding, which could potentially lead to novel therapeutic approaches for diabetes treatment."
7. Use it in a clinical scenario: To demonstrate the practical application of the word or phrase, you can incorporate it into a clinical scenario.
For example, "The patient's proinsulin levels were found to be elevated, indicating a potential impairment in insulin processing and secretion."
8. Compare it to other related terms: To further clarify the meaning of proinsulin, you can compare it to other related terms such as insulin or C-peptide.
For example, "Unlike insulin, which is the active hormone responsible for glucose uptake, proinsulin serves as a precursor that requires enzymatic processing to become biologically active." Remember, when using the word "proinsulin" or the phrase "proinsulin protein" in a sentence, it is crucial to ensure that the context and meaning are clear to your audience. By following these tips, you can effectively incorporate this term into your writing and enhance the overall understanding of its significance in diabetes management and research.
The word usage examples above have been gathered from various sources to reflect current and historical usage of the word Proinsulin. They do not represent the opinions of TranslateEN.com.